Basically the ASUS Maximus VI Gene's Layout has been very well thought. Once more practical are the angled SATA connectors as well as the power- and reset-buttons. There is also a debug display which is very useful in case you should have issues with a component in your system or the board itself. Especially overclockers will enjoy the voltage read-out points. Regarding the PCI-Express x16 slots there we have nothing to complain about. A closer look at the area around the CPU socket shows, that there is plenty of space to install big aircoolers without running into any issues. What we also liked is where the power and reset buttons are. Especially when you overclock memory using liquid nitrogen, then it makes sense to not have them next to the DIMM slots, since they will free quite quickly. Another great addition is the mPCIe-Slot, which in this case is compatible with M.2 (NGFF) SSDs. Unfortunately this slot has only been wired to one PCI Express 2.0 x1 lane, which means, that maximum transfer speeds won't surpass 500 Megabyte per second.