Generally the ASUS P8Z77-V Deluxe's Layout is well thought. Once more very practical are the angled SATA connectors as well as the power- and reset-buttons. Also the debug display is very useful in case you should have issues with a component in your system or the board itself. Furthermore the placement of the PCI-Express x16 slots is also well thought an therefore nothing needs to be criticized at this point. Unfortunately as we already phrased out in the text above there are some issues if you focus on the CPU socket. The aluminium blocks which keep the current converters cool can cause compatibility problems with high end CPU coolers. Another thing is the DIMM slots. They are also very close to the socket. In this case memory which is equipped with big heatspreaders can also collide with big aircoolers.