Generally the ASUS P8B WS's Layout has been well thought. Once more practical are the angled SATA connectors as well as the power- and reset-buttons which can be found on an additional diagnosis card. Furthermore it is possible to install a total of four graphics cards. Unfortunately one can only build a CrossFire multi GPU setup and therefore your limited to applications which cause high open GL loads. A closer look at the area around the CPU socket reveals that there is plenty of space to install any big CPU cooler. The fact that the cooling blocks are much smaller makes it easy to install a CPU cooler too.  the placement of the third PCI-Express slot isn't perfect. We would have love to see it as the second last expansion sloat onboard but in with the P8B WS it is the last and therefore when a dual slot video card is being installed in the last PCI-Express x16 slot it will cover the connectors at the bottom edge of the board. Unfortunately as we already phrased out in the text above there are some issues if you focus on the CPU socket. The aluminium blocks which keep the current converters cool can cause compatibility problems with high end CPU coolers. Another thing is the DIMM slots. They are also very close to the socket. In this case memory which is equipped with big heatspreaders can also collide with big aircoolers.