Generally the ASRock Extreme7 Gen3's Layout has been very well thought. Once more practical are the angled SATA connectors of which you'll find a total of ten. Furhtermore there also are very useful power- and reset-buttons. There even is a debug display which is very convenient in case you should have issues with a component in your system or the board itself. Altogether there are five PCI-Express x16 slots. No wonder that one was placed at the bottom edge of the board. In this case you should be aware that if you plan on putting a garphics card into the last PCI-Express x16 slot you'll block the connectors at the bottom edge of the board. Fortunately you have four other slots to put GPUs in. If a big CPU cooler needs to be placed onto the Extreme7 Gen3 this is also possible. Although the cooling blocks are quite big, there are no compatibility issues. Last but not least, overclockers will enjoy the additional molex power connector which supports the current supply regarding overclocked graphics cards.