Soo in the end everything found the right place inside! Between the cooler and the DDR4 there is enough space, you can even push the fan very low since there are few millimeter of clearance. The GPU fits in a very nice way, despite on front there is the huge USB3.0 cable, I still have enough space for a good cable management. Since this motherboard feature a M.2 Slot on the back, I suggest to equip it in order to have less cables as possible around. The downside of the MSI Z170I Gaming Pro AC is the compatibility with SSD M.2 since there is space only for SSD with total lenght of 60mm (2260) that are not so common.